Omega-3 fatty acids reduce the risk of coronary heart disease? The latest research does not think so

Previous studies have found that omega-3 fatty acids can prevent or reduce the development of cardiovascular disease. Some associations and guidelines also recommend increasing the intake of omega-3 fatty acids in the population. However, a meta-analysis published by JAMA Cardiology on January 31 showed that omega-3 fatty acids neither reduced nor increased the risk of fatal or nonfatal coronary heart disease or major vascular events in high-risk patients.

Omega-3 fatty acids reduce the risk of coronary heart disease? The latest research does not think so

The researchers analyzed data from 77,917 patients (mean age 64 years, 61% males) from 10 clinical trials.

The meta-analysis included randomized clinical trials or open randomized controlled trials comparing marine-derived long-chain omega-3 fatty acid supplements with placebo. The trial included at least 500 patients and the treatment time was over 1 year.

Predicted endpoints include death from coronary heart disease, nonfatal myocardial infarction, coronary or non-coronary revascularization events, major vascular events, all-cause death, and stroke with hemorrhagic, ischemic, and difficult-to-classify causes.